Lipidomics analysis

Author
Affiliation

Daniel Ibsen

Steno Diabetes Center Aarhus

Basic statistics

Descriptive statistics of the metabolites.
Metabolite Mean SD
CDCl3 (solvent) 180 (67)
Cholesterol 18.6 (11.4)
FA -CH2CH2COO- 33.6 (7.8)
Lipid -CH2- 536.6 (61.9)
Lipid CH3- 1 98.3 (73.8)
Lipid CH3- 2 168.2 (29.2)
MUFA+PUFA 32.9 (16.1)
PUFA 30 (24.1)
Phosphatidycholine 31.7 (20.5)
Phosphatidylethanolamine 10 (7.6)
Phospholipids 2.7 (2.6)
TMS (interntal standard) 123 (130.4)

Creating figure of metabolite levels

`stat_bin()` using `bins = 30`. Pick better value with `binwidth`.

Table of model estimates

Estimates of metabolites
Metabolite Estimate Standard error p-value
TMS (interntal standard) 0.056 0.990 0.004
Cholesterol 2.968 0.458 0.017
Lipid CH3- 1 44.473 1.406 0.007
Lipid CH3- 2 0.885 0.361 0.734
Lipid -CH2- 0.003 3.139 0.058
FA -CH2CH2COO- 1.524 0.387 0.276
PUFA 3.269 0.560 0.034
Phosphatidylethanolamine 26.881 1.324 0.013
Phosphatidycholine 0.000 116628.112 0.998
Phospholipids 0.000 68964.221 1.000
MUFA+PUFA 0.456 0.449 0.080
CDCl3 (solvent) 0.087 0.865 0.005

Figure of model estimates